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Biotransformation of the tetracyclines seems to be limited in most domestic animalsand generally about one-third of a given dose is excreted unchangedRolitetracycline is metabolized to tetracyclineDoxycycline and minocycline may be more extensively biotransformed than other tetracyclinesup to 40of a given dose
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TABLE IIMetal complexes as binders using tetracyclinePereira-Maia et al.2010)
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for the diffusion technique, the 30-mcg tetracycline or minocin disk should provide the following zone diameters in these laboratory test quality control strains .