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Take exactly as prescribed by your doctorDo not take in larger or smaller amounts or for longer colchicine. than recommendedFollow the directions on your prescription label.
Zofran and other 5-GT3 receptor antagonists are considered antiemetic agentsThese are any drugs that prevent vomiting or nausea including over-the-counter antihistaminesBenadrylDramamineor bismuth subsalicylatePepto-BismolKaopectate
Ondansetron does not itself appear to induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system of the liversee CLINICAL PHARMACOLOGYBecause ondansetron is metabolized by hepatic cytochrome P450 drug-metabolizing enzymesCYP3A4CYP2D6CYP1A2inducers or inhibitors of these enzymes may change the clearance andhencethe half-life of ondansetronIn patients treated with potent inducers of CYP3A4i.ephenytoincarbamazepineand rifampinthe clearance of ondansetron was significantly increased and ondansetron blood concentrations were decreasedHoweveron the basis of available datano dosage adjustment for ZOFRAN is recommended for patients on these drugssee CLINICAL PHARMACOLOGY
Then administer 8 mg three times a day for 1 to 2 days after completion of chemotherapy.
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in addition, postmarketing cases of torsade de pointes have been reported in patients using zofran.