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Table 2Starting Dose for Dialysis Patients Switching From Calcium Acetate to Renagel.
Dosage should be adjusted based on the serum phosphorus concentration with a goal of lowering serum phosphorus to 5.5 mg/dL or lessThe dose may be increased or decreased by one tablet per meal at two week intervals as necessaryTable 3 gives a dose titration guidelineThe average dose in a Phase 3 trial designed to lower serum phosphorus to 5.0 mg/dL or less was approximately three Renagel 800 mg tablets per mealThe maximum average daily Renagel dose studied was 13 grams.
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