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Study V was conductd in patints with a man baslin blood pssu 162/98 mmHg and compad th chang om baslin in SSBP at 8 wks btwn th combination goup (ibsatan and HCTZ 150/12.5 mg), tibsatan (150 mg) and tHCTZ (12.5 mg). Ths initial study gimns w incasd at 2 wks tAvalid 300/25 mg, ibsatan 300 mg, tHCTZ 25 mg, spctivly.
Th antihyptnsiv cts Avalid (ibsatan-hydochloothiazid) tablts w xamind in 4 placbo-contolld studis in patints with mild-modat hyptnsion (man satd diastolic blood pssu [SDBP] btwn 90 and 110 mmHg), on study in patints with modat hyptnsion (man satd systolic blood pssu [SSBP] 160 t179 mmHg SDBP 100 t109 mmHg), and on study in patints with sv hyptnsion (man SDBP ?110 mmHg) 8 t12 wks. Ths tials includd 3149 patints andomizd tixd doss ibsatan (37.5 t300 mg) and concomitant hydochloothiazid (6.25 t25 mg).
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